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What medications can increase risk of osteoporosis? Medications that can Cause Bone Loss, Falls and/or Fractures Synthetic Glucocorticoids (e.g. prednisone) Breast Cancer Drugs. Prostate Cancer Drugs. "Heartburn" Drugs. Depo-Provera. Excessive Thyroid Hormone Replacement. Anti-seizure and Mood-altering Drugs. Blood Pressure Medication.
How effective is Prolia for osteoporosis? Clinical trials found Prolia just as effective (but really no more effective) than bisphosphonates, which are the current standard for osteoporosis care. "The way that denosumab (Prolia) works is that it's a fully human monoclonal antibody to RANK ligand.
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